function_based_analysis
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function_based_analysis [2015/12/28 11:04] mhidalgo |
function_based_analysis [2020/04/03 20:18] (current) |
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| * **Heatmap**: A heatmap is a graphical representation of the values of a matrix. A not-supervised clustering is performed on the data per columns (samples). A good separation between the two colors of the upper bar of the heatmap indicates that the differences between the two groups are big enough to discriminate between them. | * **Heatmap**: A heatmap is a graphical representation of the values of a matrix. A not-supervised clustering is performed on the data per columns (samples). A good separation between the two colors of the upper bar of the heatmap indicates that the differences between the two groups are big enough to discriminate between them. | ||
| * **PCA**: A Principal Components Analysis is performed in order to see if the matrix contains information enough to separate between the two groups. | * **PCA**: A Principal Components Analysis is performed in order to see if the matrix contains information enough to separate between the two groups. | ||
| - | * **Circuit significance**: Ordered table of the functions significance. More significant terms are displayed in the upper part of the table. For each functional term, the following information is shown: | + | * **GO terms/Uniprot keywords significance**: Ordered table of the functions significance. More significant terms are displayed in the upper part of the table. For each functional term, the following information is shown: |
| * **path/term**: Name of the function. | * **path/term**: Name of the function. | ||
| * **UP/DOWN**: Up when the function is up-regulated in the disease case, DOWN otherwise. | * **UP/DOWN**: Up when the function is up-regulated in the disease case, DOWN otherwise. | ||
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| * **p.value**: P-value of the statistic test. | * **p.value**: P-value of the statistic test. | ||
| * **FDRp.value**: Adjusted p-value of the statistic test using the FDR method. | * **FDRp.value**: Adjusted p-value of the statistic test using the FDR method. | ||
| + | * **Fold Change** | ||
| + | * **logFC** | ||
function_based_analysis.1451300641.txt.gz ยท Last modified: 2020/04/03 20:18 (external edit)
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