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path_values [2015/12/21 17:14]
mhidalgo
path_values [2020/04/03 20:18] (current)
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-====== ​Path values ======+====== ​Circuit ​values ======
  
-Here you will find descriptive information about the matrix of pathway ​values.+Here you will find descriptive information about the matrix of circuit/​path ​values.
  
-  * **Path values**: You can download the matrix of path values by clicking on //Path values//.+  * **Path values**: You can download the matrix of circuit ​values by clicking on //Path values//.
   * **Heatmap**:​ A heatmap is a graphical representation of the values of a matrix. A not-supervised clustering is performed on the data per columns (samples). A good separation between the two colors of the upper bar of the heatmap indicates that the differences between the two groups are big enough to discriminate between them.   * **Heatmap**:​ A heatmap is a graphical representation of the values of a matrix. A not-supervised clustering is performed on the data per columns (samples). A good separation between the two colors of the upper bar of the heatmap indicates that the differences between the two groups are big enough to discriminate between them.
   * **PCA**: A Principal Components Analysis is performed in order to see if the matrix contains information enough to separate between the two groups. ​   * **PCA**: A Principal Components Analysis is performed in order to see if the matrix contains information enough to separate between the two groups. ​
-  * **Path significance**:​ Ordered table of pathway ​significance. More significant ​pathways ​are displayed in the upper part of the table. For each pathway, the following information is shown: +  * **Path significance**:​ Ordered table of circuit ​significance. More significant ​circuits ​are displayed in the upper part of the table. For each circuit, the following information is shown: 
-    * **path/term**: Code identifying the path consisting in the name of the pathway to which it belongs, the initial node (if //Decompose paths// option was selected) ​and the effector (last) node of the path. +    * **circuit/term**: Code identifying the circuit ​consisting in the name of the pathway to which it belongs and the effector (last) node of the path (//pathway Name : Effector//)
-    * **UP/​DOWN**:​ Up when the path is up-regulated in the disease case, DOWN otherwise. +    * **UP/​DOWN**:​ Up when the circuit ​is up-regulated in the disease case, DOWN otherwise. 
-    * **statistic**:​ Statistic of the of the statistic ​test.+    * **statistic**:​ Statistic of the Wilcoxon ​test performed between conditions.
     * **p.value**:​ P-value of the statistic test.     * **p.value**:​ P-value of the statistic test.
     * **FDRp.value**:​ Adjusted p-value of the statistic test using the FDR method.     * **FDRp.value**:​ Adjusted p-value of the statistic test using the FDR method.
 +    * **Fold Change**: is a measure describing how much the ** circuit activity** changes between conditions.[[https://​en.wikipedia.org/​wiki/​Fold_change|reed more about Fold Change]]
 +    * **logFC**: The logarithm to base 2 of calculated Fold change.
path_values.1450718057.txt.gz · Last modified: 2020/04/03 20:18 (external edit)