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path_values [2018/12/26 20:02]
krian
path_values [2020/04/03 20:18] (current)
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   * **PCA**: A Principal Components Analysis is performed in order to see if the matrix contains information enough to separate between the two groups. ​   * **PCA**: A Principal Components Analysis is performed in order to see if the matrix contains information enough to separate between the two groups. ​
   * **Path significance**:​ Ordered table of circuit significance. More significant circuits are displayed in the upper part of the table. For each circuit, the following information is shown:   * **Path significance**:​ Ordered table of circuit significance. More significant circuits are displayed in the upper part of the table. For each circuit, the following information is shown:
-    * **circuit/​term**:​ Code identifying the circuit consisting in the name of the pathway to which it belongs, the initial node (if //Decompose paths// option was selected) ​and the effector (last) node of the path.+    * **circuit/​term**:​ Code identifying the circuit consisting in the name of the pathway to which it belongs and the effector (last) node of the path (//pathway Name : Effector//).
     * **UP/​DOWN**:​ Up when the circuit is up-regulated in the disease case, DOWN otherwise.     * **UP/​DOWN**:​ Up when the circuit is up-regulated in the disease case, DOWN otherwise.
     * **statistic**:​ Statistic of the Wilcoxon test performed between conditions.     * **statistic**:​ Statistic of the Wilcoxon test performed between conditions.
     * **p.value**:​ P-value of the statistic test.     * **p.value**:​ P-value of the statistic test.
     * **FDRp.value**:​ Adjusted p-value of the statistic test using the FDR method.     * **FDRp.value**:​ Adjusted p-value of the statistic test using the FDR method.
 +    * **Fold Change**: is a measure describing how much the ** circuit activity** changes between conditions.[[https://​en.wikipedia.org/​wiki/​Fold_change|reed more about Fold Change]]
 +    * **logFC**: The logarithm to base 2 of calculated Fold change.
path_values.1545854549.txt.gz ยท Last modified: 2020/04/03 20:17 (external edit)