what_can_do_hipathia_for_you
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what_can_do_hipathia_for_you [2020/02/03 13:32] – krian | what_can_do_hipathia_for_you [2020/02/06 15:55] – [Hipathia mechanism] krian | ||
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In order to calculate the circuit signal, once the node activity values have been estimated, we assume an incoming signal value of 1 in the input nodes (stimuli-receptor proteins) of any circuit. Then, the signal is propagated to the following nodes as shown in the image above until it reaches its effector node. This is going to be the values that will be taken as the activation value for each " | In order to calculate the circuit signal, once the node activity values have been estimated, we assume an incoming signal value of 1 in the input nodes (stimuli-receptor proteins) of any circuit. Then, the signal is propagated to the following nodes as shown in the image above until it reaches its effector node. This is going to be the values that will be taken as the activation value for each " | ||
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Finally, Hipathia also calculates the activation state of some molecular functions by looking at the functions annotated for the effector proteins in which the " | Finally, Hipathia also calculates the activation state of some molecular functions by looking at the functions annotated for the effector proteins in which the " | ||
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This video present a simple simulation of how Hipathia model calculate the propagated signal throw a signaling circuit: | This video present a simple simulation of how Hipathia model calculate the propagated signal throw a signaling circuit: | ||
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The HiPathia web server integrates four different pathway analysis modules: | The HiPathia web server integrates four different pathway analysis modules: | ||
* **Differential signaling** | * **Differential signaling** |
what_can_do_hipathia_for_you.txt · Last modified: 2021/01/05 15:49 by krian