====== Mutation impact ======

This panel only appears when a **VCF file has been selected**. In this case, we need to specify some further parameters:
  * **Reference genome**: Select either reference genome GRCh37 or GRCh38
  * **Inheritance pattern**: Select the kind of inheritance pattern, either recessive or dominant.
  * **Compound hetero**: Select if heterozygote compounds must be considered.
  * **SIFT, PolyPhen, PhastCons**: Select which tools must be used in order to infer the impact of the mutations in the expression profile. At least one of them must be selected.