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--- worked_example_perturbation_effect [2019/08/08 16:31]
krian
+++ worked_example_perturbation_effect [2020/10/16 16:02] (current)
krian
@@ Line 12: / Line 12: @@
   * Select the genes whose you want to modify its expression value. You can either click on a gene on the pathway viewer and change its value.
 {{ :perturbationeffectexamplechangevalue1.png |}}
-or search it in the Search genes… box of the Gene list panel.
+or search it in the Search genes… box of the Add genes panel.
-{{ :searchgene.png |}}
+{{ :drug.mp4?900 |}}
-  *
+  *  You can modify the expression level of the genes listed in the Add genes panel and remove them from the list by pressing the **X** button to their right. The expression level of the removed genes will return to their original value.
+For this example we fix the following expression values:
+     * IL6
+{{ :addgenesexample.png |}}
+  * Select the drugs targeting the objective genes if desired. We selected the "Siltuximab" drug for this example.
+  * Press the Update button from the Gene list panel.{{ :updatebtn.png |}}
+The comparison is performed and the results prepared.
+{{ :loadingperturbationeffectstudy.png |}}
+  * Visualize the results. For further information in the interpretation of the results, see [[Perturbation effect results|Perturbation effect results]].

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