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what_can_do_hipathia_for_you [2021/01/05 15:48] – [Variant interpreter] krianwhat_can_do_hipathia_for_you [2021/01/05 15:49] (current) – [Differential signaling] krian
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 {{ ::hipathiatools.png |http://hipathia.babelomics.org}}   {{ ::hipathiatools.png |http://hipathia.babelomics.org}}  
  
-===== Differential signaling =====+==== Differential signaling ====
  
 This module provides an estimation of the significant cell signaling activity changes across different conditions. To achieve so, signal value activities are estimated for each signaling circuit for the studied samples. Then, these signaling activity profiles can be **compared** according to the experimental design of the used dataset: This module provides an estimation of the significant cell signaling activity changes across different conditions. To achieve so, signal value activities are estimated for each signaling circuit for the studied samples. Then, these signaling activity profiles can be **compared** according to the experimental design of the used dataset:
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 See the [[differential_signaling|Differential signaling]] tool. See the [[differential_signaling|Differential signaling]] tool.
-===== Prediction =====+==== Prediction ====
  
 HiPathia allows you to train, download and test a prediction model for your dataset. The machine learning module can be trained either to: HiPathia allows you to train, download and test a prediction model for your dataset. The machine learning module can be trained either to:
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 In order to check how to use these tool please see [[Prediction|Prediction]]. In order to check how to use these tool please see [[Prediction|Prediction]].
  
-===== Perturbation effect =====+==== Perturbation effect ====
  
 This module offers an interactive working environment to simulate the effect of different interventions (e.g. knock-out, over-expression, etc.) over the activity of signaling circuits in the pathways, as well as their potential functional consequences in the cell. Given a specific condition, corresponding to a specific gene expression profile, knock-outs, knock-downs or different types of inhibitions are simulated by reducing or setting to 0 the expression level of the gene or interest.  This module offers an interactive working environment to simulate the effect of different interventions (e.g. knock-out, over-expression, etc.) over the activity of signaling circuits in the pathways, as well as their potential functional consequences in the cell. Given a specific condition, corresponding to a specific gene expression profile, knock-outs, knock-downs or different types of inhibitions are simulated by reducing or setting to 0 the expression level of the gene or interest. 
what_can_do_hipathia_for_you.1609861732.txt.gz · Last modified: 2021/01/05 15:48 by krian